Late-Onset Movement Disorders Are More Common After Stroke in the Era of Thrombectomy, Thrombolysis

Background: Late-onset movement disorders after acute ischemic stroke (AIS) are historically reported in 1% to 4% of cases, often under recognized due to delayed onset. Mechanical thrombectomy (MT) and thrombolysis have altered infarct patterns, increasing the proportion of survivors with basal ganglia (BG) infarcts without major motor pathway involvement, potentially raising risk. Objective: To determine the 1-year incidence and characterize the spectrum of movement disorders that develop after AIS treated with IV thrombolysis (IVT), MT, or both, and to evaluate how infarct patterns, especially BG involvement, influence risk. Design: Retrospective cohort study was conducted at a tertiary care Comprehensive Stroke Center. Investigators used a vascular neurology registry to identify consecutive patients hospitalized for AIS between 2016 and 2022. Participants/Methods: Eligible patients were adults aged ≥18 years who received IVT, MT, or both, and who had at least 1 outpatient neuro more...